Mauricio Pochettino talked in his after game press conference about the internationals causing problems, he spoke about it at an earlier press conference regarding the September internationals too.
The game is no longer about eleven men on a pitch, it is very much a squad game now and you need a squad size that can handle it. Pochettino prefers a smaller squad so everyone remains involved, but that can mean stretching our resources at times. Kane twists his ankle and we are left with one striker. Do we not need either an experienced striker or do we rely on a youngster, in this case, Shayon Harrision, who doesn't really look ready for Premier League football yet.
You wouldn't want Janssen to pick up an injury otherwise, it is either Harrison or moving Son to play the lone striker. We do appear at times to be walking a tightrope.
"We will find out tomorrow (Monday), Harry twisted his ankle and he felt pain in it. It could be a problem with his ligament but today is difficult to assess and give an opinion.
"It is difficult without him, but we signed Janssen, he’s working very well and he is a striker that can give us a lot of things.
"When you are involved in different competitions like the Champions League, it’s a new competition for us and we spent a lot of energy on Wednesday.
"It was different from the last two seasons when we were only playing in the Europa League, where we could rotate the squad and the starting eleven.
"It’s new for us, and it’s important to learn, and sometimes you are surprised when you make changes.
"All our internationals had a difficult summer, they played in the Euros, and it’s more difficult to get fit."